The existing solutions do not consider applying web visualization and three-dimensional (3D) volume rendering methods simultaneously to reduce the number of data copy operations and provide a better way to visualize 3D structures in bioimage data. Visualizing or interacting with these massive data is both necessary and essential in the bioimage analysis pipeline however, due to their size, researchers have difficulty using typical computers to process them. The popularity of mesoscopic whole-brain imaging techniques has increased dramatically, but these techniques generate teravoxel-sized volumetric image data. 5HUST-Suzhou Institute for Brainsmatics, JITRI Institute for Brainsmatics, Suzhou, China.4MoE Key Laboratory for Biomedical Photonics, School of Engineering Sciences, Huazhong University of Science and Technology, Wuhan, China.3Wuhan National Laboratory for Optoelectronics, Britton Chance Center for Biomedical Photonics, Huazhong University of Science and Technology, Wuhan, China.2Shaanxi Key Laboratory of Network Computing and Security Technology, Xi'an, China.1School of Computer Science and Engineering, Xi'an University of Technology, Xi'an, China.Yuxin Li 1,2 *, Anan Li 3,4,5 *, Junhuai Li 1,2, Hongfang Zhou 1,2, Ting Cao 1,2, Huaijun Wang 1,2 and Kan Wang 1,2
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